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Antibody Product Overview
| ELK.No | ES14281 |
| Product name | PACE1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 57147 |
| Human Swiss-Prot | Q8IZE3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PACE1 |
| Fields | |
| Gene name | SCYL3 PACE1 |
| Protein name | PACE1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 240880 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9DBQ7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PACE1 AA range: 519-569 |
| Specificity | This antibody detects endogenous levels of PACE1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 82kD |
| Observed band (KD) | |
| Background | This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012], |
| Function | domain:The protein kinase domain is predicted to be catalytically inactive.,function:May play a role in regulating cell adhesion/migration complexes in migrating cells.,PTM:May be myristoylated; myristoylation may target it to Golgi compartment.,PTM:Phosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 4 HEAT repeats.,subcellular location:Colocalized with EZR/VIL2, actin and CD44 in lamellipodia.,subunit:Interacts with EZR/VIL2 C-terminal domain.,tissue specificity:Ubiquitously expressed., |
| Subcellular location | Cytoplasm . Golgi apparatus . Cell projection, lamellipodium . Colocalized with EZR/VIL2, actin and CD44 in lamellipodia. |
| Expression | Ubiquitously expressed. |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14281-100
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