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Antibody Product Overview
| ELK.No | ES14440 |
| Product name | NUCB1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4924 |
| Human Swiss-Prot | Q02818 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NUCB1 |
| Fields | |
| Gene name | NUCB1 NUC |
| Protein name | NUCB1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18220 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q02819 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 84595 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q63083 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human NUCB1 AA range: 54-104 |
| Specificity | This antibody detects endogenous levels of NUCB1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 51kD |
| Observed band (KD) | |
| Background | This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010], |
| Function | domain:The EF-hand domains are unfolded in the absence of Ca(2+) and fold upon Ca(2+) addition.,function:Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis.,miscellaneous:Discovered as DNA-binding protein in the serum of lupus-prone mice.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the nucleobindin family.,similarity:Contains 2 EF-hand domains.,subcellular location:A small fraction of the protein may be cytoplasmic.,subunit:Interacts with GNAI2 and GNAI3.,tissue specificity:Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas., |
| Subcellular location | Golgi apparatus, cis-Golgi network membrane ; Peripheral membrane protein ; Lumenal side . Cytoplasm . Secreted . A small fraction of the protein may be cytoplasmic. . |
| Expression | Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas. |
Additional Images
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Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14440-50
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