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Antibody Product Overview
| ELK.No | ES14457 |
| Product name | NPNT rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain) (Protein EGFL6-like) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 255743 |
| Human Swiss-Prot | Q6UXI9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NPNT |
| Fields | >>ECM-receptor interaction |
| Gene name | NPNT EGFL6L POEM UNQ295/PRO334 |
| Protein name | NPNT |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 114249 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q91V88 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human NPNT AA range: 485-535 |
| Specificity | This antibody detects endogenous levels of NPNT at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.126% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | |
| Function | developmental stage:Expressed in fetal kidney, cochlea, eye, heart and lung.,domain:The MAM domain is required for localization at the cell surface.,function:Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.,similarity:Belongs to the nephronectin family.,similarity:Contains 1 MAM domain.,similarity:Contains 5 EGF-like domains.,subcellular location:Trapped on the cell surface or in the extracellular matrix.,subunit:Homodimer and homotrimer.,tissue specificity:Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels., |
| Subcellular location | Secreted, extracellular space, extracellular matrix . Trapped on the cell surface or in the extracellular matrix. . |
| Expression | Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14457-50
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