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Antibody Product Overview
| ELK.No | ES14718 |
| Product name | MPPB rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9512 |
| Human Swiss-Prot | O75439 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MPPB |
| Fields | |
| Gene name | PMPCB MPPB |
| Protein name | MPPB |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 73078 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CXT8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 64198 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q03346 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human MPPB AA range: 92-142 |
| Specificity | This antibody detects endogenous levels of MPPB at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 54kD |
| Observed band (KD) | |
| Background | This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.,cofactor:Binds 1 zinc ion per subunit.,function:Cleaves presequences (transit peptides) from mitochondrial protein precursors.,similarity:Belongs to the peptidase M16 family.,subunit:Heterodimer of alpha and beta subunits., |
| Subcellular location | Mitochondrion matrix . |
| Expression |
Additional Images
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Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14718-50
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