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Antibody Product Overview
| ELK.No | ES14922 |
| Product name | MMS19 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 64210 |
| Human Swiss-Prot | Q96T76 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MMS19 |
| Fields | |
| Gene name | MMS19 MMS19L |
| Protein name | MMS19 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 72199 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9D071 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human MMS19 AA range: 653-703 |
| Specificity | This antibody detects endogenous levels of MMS19 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 113kD |
| Observed band (KD) | |
| Background | |
| Function | function:May play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types.,similarity:Belongs to the MET18/MMS19 family.,similarity:Contains 7 HEAT repeats.,subunit:Interacts with ERCC2/XPD, ERCC3/XPB and NCOA3/RAC3.,tissue specificity:Ubiquitously expressed with higher expression in testis., |
| Subcellular location | Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . In mitosis, enriched on centrosomes during prophase, localizes to the spindle during metaphase and surrounds compacted spindle midzone microtubules during telophase. . |
| Expression | Ubiquitously expressed with higher expression in testis. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14922-50
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