Français
English
Antibody Product Overview
| ELK.No | ES14949 |
| Product name | MICA1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 64780 |
| Human Swiss-Prot | Q8TDZ2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MICA1 |
| Fields | |
| Gene name | MICAL1 MICAL NICAL |
| Protein name | MICA1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 171580 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8VDP3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 294520 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | D3ZBP4 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human MICA1 AA range: 155-205 |
| Specificity | This antibody detects endogenous levels of MICA1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 117kD |
| Observed band (KD) | |
| Background | This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015], |
| Function | cofactor:FAD .,domain:The C-terminal coiled coil part contains the plexin-interacting region.,function:May be a cytoskeletal regulator that connects NEDD9 to intermediate filaments.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 LIM zinc-binding domain.,subunit:Associates with the SH3 domain of NEDD9. Interacts with VIM and PLXNA3. Interacts with RAB1B.,tissue specificity:Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells., |
| Subcellular location | Cytoplasm. Cytoplasm, cytoskeleton. Midbody . Accumulates transiently at the abscission site before abscission occurs. . |
| Expression | Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells. |
Additional Images
No image
Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
No image
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
No image
No image
: AO-06-ES14949-100
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package