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Antibody Product Overview
| ELK.No | ES14960 |
| Product name | METK2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4144 |
| Human Swiss-Prot | P31153 |
| Source | Rabbit |
| Isotype | IgG |
| Target | METK2 |
| Fields | >>Cysteine and methionine metabolism;>>Metabolic pathways;>>Biosynthesis of amino acids;>>Biosynthesis of cofactors |
| Gene name | MAT2A AMS2 MATA2 |
| Protein name | METK2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 232087 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q3THS6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 171347 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P18298 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human METK2 AA range: 294-344 |
| Specificity | This antibody detects endogenous levels of METK2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 43kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011], |
| Function | catalytic activity:ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine.,cofactor:Binds 1 potassium ion per subunit.,cofactor:Binds 2 divalent ions per subunit. Magnesium or cobalt.,function:Catalyzes the formation of S-adenosylmethionine from methionine and ATP.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,PTM:The alpha' subunit is a post-translationally modified version of MAT2A.,similarity:Belongs to the AdoMet synthetase family.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B)., |
| Subcellular location | cytosol,methionine adenosyltransferase complex, |
| Expression | Detected in kidney. |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14960-100
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