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Antibody Product Overview
| ELK.No | ES14985 |
| Product name | MECR rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 51102 |
| Human Swiss-Prot | Q9BV79 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MECR |
| Fields | >>Fatty acid biosynthesis;>>Fatty acid elongation;>>Metabolic pathways;>>Fatty acid metabolism |
| Gene name | MECR NBRF1 CGI-63 |
| Protein name | MECR |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 26922 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9DCS3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29470 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9Z311 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human MECR AA range: 160-210 |
| Specificity | This antibody detects endogenous levels of MECR at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 41kD |
| Observed band (KD) | |
| Background | |
| Function | catalytic activity:Acyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.,function:Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,subunit:Homodimer.,tissue specificity:Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung., |
| Subcellular location | [Isoform 1]: Mitochondrion .; [Isoform 2]: Cytoplasm . Nucleus . |
| Expression | Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung. |
Additional Images
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Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14985-100
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