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Antibody Product Overview
| ELK.No | ES15139 |
| Product name | LMF1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Lipase maturation factor 1 (Transmembrane protein 112) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 64788 |
| Human Swiss-Prot | Q96S06 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LMF1 |
| Fields | |
| Gene name | LMF1 C16orf26 TMEM112 HMFN1876 JFP11 |
| Protein name | LMF1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 76483 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q3U3R4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human LMF1 AA range: 257-307 |
| Specificity | This antibody detects endogenous levels of LMF1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.144% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | The protein encoded by this gene resides in the endoplasmic reticulum, and is involved in the maturation and transport of lipoprotein lipase through the secretory pathway. Mutations in this gene are associated with combined lipase deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010], |
| Function | disease:Defects in LMF1 are the cause of combined lipase deficiency (CLD) [MIM:246650]. CLD is characterized by repeated episodes of pancreatitis, tuberous xanthomas and lipodystrophy and is caused by deficiency of both lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL).,function:Involved in the maturation of specific proteins in the endoplasmic reticulum. Required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway.,similarity:Belongs to the lipase maturation factor family., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Expression | Hepatoblastoma,Kidney epithelium,Pancreas,Teratocarcinoma,Testis, |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15139-50
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