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Antibody Product Overview
| ELK.No | ES15154 |
| Product name | LIPA4 rabbit pAb |
| Reactivity | Human;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 8497 |
| Human Swiss-Prot | O75335 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LIPA4 |
| Fields | |
| Gene name | PPFIA4 KIAA0897 |
| Protein name | LIPA4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | 140592 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q91Z80 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human LIPA4 AA range: 513-563 |
| Specificity | This antibody detects endogenous levels of LIPA4 at Human/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 77kD |
| Observed band (KD) | |
| Background | PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; MIM 611054) for background on liprins.[supplied by OMIM, Mar 2008], |
| Function | domain:The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.,function:May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.,similarity:Belongs to the liprin family. Liprin-alpha subfamily.,similarity:Contains 3 SAM (sterile alpha motif) domains.,subcellular location:Colocalizes with PTPRF at the cell surface.,subunit:Forms homodimers and heterodimers with liprins-alpha and liprins-beta. Interacts with the second PTPase domain of PTPRD, PTPRF and PTPRS. Binds RIMS1, RIMS2, GIT1, KIF1A and GRIP1.,tiss |
| Subcellular location | Cytoplasm . Cell surface . Colocalizes with PTPRF at the cell surface. . |
| Expression | Expressed only in the heart, brain, and skeletal muscle. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15154-50
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