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Antibody Product Overview
| ELK.No | ES15174 |
| Product name | LCTL rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 197021 |
| Human Swiss-Prot | Q6UWM7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LCTL |
| Fields | |
| Gene name | LCTL KLPH UNQ3022/PRO9820 |
| Protein name | LCTL |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 235435 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K1F9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human LCTL AA range: 450-500 |
| Specificity | This antibody detects endogenous levels of LCTL at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.143% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013], |
| Function | caution:Probably inactive as a glycosidase since it lacks the essential active site Glu at position 201.,similarity:Belongs to the glycosyl hydrolase 1 family.,similarity:Belongs to the glycosyl hydrolase 1 family. Klotho subfamily., |
| Subcellular location | Endoplasmic reticulum membrane ; Single-pass membrane protein . |
| Expression |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15174-50
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