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Antibody Product Overview
| ELK.No | ES15178 |
| Product name | LCMT2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9836 |
| Human Swiss-Prot | O60294 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LCMT2 |
| Fields | |
| Gene name | LCMT2 KIAA0547 TYW4 |
| Protein name | LCMT2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 329504 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BYR1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 296098 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5XIA3 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human LCMT2 AA range: 298-348 |
| Specificity | This antibody detects endogenous levels of LCMT2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 75kD |
| Observed band (KD) | |
| Background | The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008], |
| Function | function:Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.,pathway:tRNA modification; wybutosine-tRNA(Phe) biosynthesis.,similarity:Belongs to the methyltransferase superfamily. LCMT family.,subunit:Interacts with RNF144B/IBRDC2., |
| Subcellular location | cytoplasm,cytosol, |
| Expression |
Additional Images
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Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES15178-50
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