| ELK.No | ES15192 |
| Product name | LAT4 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 124935 |
| Human Swiss-Prot | Q8N370 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LAT4 |
| Fields | |
| Gene name | SLC43A2 LAT4 PP7664 |
| Protein name | LAT4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 215113 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8CGA3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human LAT4 AA range: 122-172 |
| Specificity | This antibody detects endogenous levels of LAT4 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.167% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | This gene encodes a member of the L-amino acid transporter-3 or SLC43 family of transporters. The encoded protein mediates sodium-, chloride-, and pH-independent transport of L-isomers of neutral amino acids, including leucine, phenylalanine, valine and methionine. This protein may contribute to the transfer of amino acids across the placental membrane to the fetus. [provided by RefSeq, Mar 2016], |
| Function | function:Sodium-, chloride, pH-independent high affinity transport of large neutral amino acids.,PTM:Glycosylated.,similarity:Belongs to the SLC43A transporter (TC 2.A.1.44) family.,tissue specificity:Detected in several tissues with, higher expression in placenta, kidney and peripheral blood leukocytes. In the kidney is detected in epithelial cells of the distal tubule and collecting duct. In the intestin is expressed mainly in crypt cells of the intestinal microvilli ans epithelial cells in the base of the villus., |
| Subcellular location | Membrane ; Multi-pass membrane protein . |
| Expression | Detected in several tissues with higher expression in placenta, kidney and peripheral blood leukocytes. In the kidney, is detected in epithelial cells of the distal tubule and collecting duct. In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus. |

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