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Antibody Product Overview
| ELK.No | ES15255 |
| Product name | KRA14 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 728255 |
| Human Swiss-Prot | P0C5Y4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KRA14 |
| Fields | |
| Gene name | KRTAP1-4 KAP1.4 KRTAP1.4 |
| Protein name | KRA14 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 23927 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O08640 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human KRA14 AA range: 5-55 |
| Specificity | This antibody detects endogenous levels of KRA14 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 13kD |
| Observed band (KD) | |
| Background | The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs), which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins (Shimomura et al., 2002 [PubMed 12228244]).[supplied by OMIM, Jan 2009], |
| Function | function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 1 family.,subunit:Interacts with hair keratins.,tissue specificity:Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone., |
| Subcellular location | keratin filament, |
| Expression | Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone. |
Additional Images
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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15255-50
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