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Antibody Product Overview
| ELK.No | ES15279 |
| Product name | KLK10 rabbit pAb |
| Reactivity | Human;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5655 |
| Human Swiss-Prot | O43240 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KLK10 |
| Fields | |
| Gene name | KLK10 NES1 PRSSL1 |
| Protein name | KLK10 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | 100911689 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P36375 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human KLK10 AA range: 199-249 |
| Specificity | This antibody detects endogenous levels of KLK10 at Human/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 30kD |
| Observed band (KD) | |
| Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008], |
| Function | developmental stage:Down-regulated during breast cancer progression.,function:Has a tumor-suppressor role for NES1 in breast and prostate cancer.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in breast, ovary and prostate., |
| Subcellular location | Secreted . |
| Expression | Expressed in breast, ovary and prostate. |
Additional Images
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Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15279-50
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