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Antibody Product Overview
| ELK.No | ES15283 |
| Product name | KLHL2 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 11275 |
| Human Swiss-Prot | O95198 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KLHL2 |
| Fields | |
| Gene name | KLHL2 |
| Protein name | KLHL2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 77113 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8JZP3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human KLHL2 AA range: 521-571 |
| Specificity | This antibody detects endogenous levels of KLHL2 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 65kD |
| Observed band (KD) | |
| Background | |
| Function | function:May play a role in organizing the actin cytoskeleton of the brain cells.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Binds actin.,tissue specificity:Predominantly expressed in brain., |
| Subcellular location | Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection . Cell projection, lamellipodium . Cytoplasm, cytosol. A proportion colocalizes with the actin cytoskeleton. When over-expressed, colocalizes with NPTXR in perinuclear aggresomes (By similarity). . |
| Expression | Ubiquitous. Detected throughout the brain. |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES15283-50
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