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Antibody Product Overview
| ELK.No | ES15293 |
| Product name | KLF2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Krueppel-like factor 2 (Lung krueppel-like factor) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10365 |
| Human Swiss-Prot | Q9Y5W3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KLF2 |
| Fields | >>FoxO signaling pathway;>>Apelin signaling pathway;>>Fluid shear stress and atherosclerosis |
| Gene name | KLF2 LKLF |
| Protein name | KLF2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 16598 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q60843 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 306330 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9ET58 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human KLF2 AA range: 196-246 |
| Specificity | This antibody detects endogenous levels of KLF2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.70% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011], |
| Function | function:Binds to the CACCC box in the beta-globin gene promoter and activates transcription.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with WWP1., |
| Subcellular location | Nucleus . |
| Expression | Brain,Hair follicle dermal papilla,Lung,Spleen, |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15293-50
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