Français
English
Antibody Product Overview
| ELK.No | ES15420 |
| Product name | ISG20 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3669 |
| Human Swiss-Prot | Q96AZ6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ISG20 |
| Fields | |
| Gene name | ISG20 HEM45 |
| Protein name | ISG20 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 57444 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JL16 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ISG20 AA range: 87-137 |
| Specificity | This antibody detects endogenous levels of ISG20 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 20kD |
| Observed band (KD) | |
| Background | |
| Function | catalytic activity:Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.,cofactor:Manganese.,function:Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.,induction:Induced by interferons alpha and beta. Weaker induction was seen with interferon gamma. Increased expression was seen at the transcriptional level.,miscellaneous:Stable and constitutive expression confers resistance to vesicular stomatitis virus (VSV), influenza virus, and encephalomyocarditis virus (EMCV) infection in HeLa cells, providing an alternative antiviral pathway against RNA genomic viruses. Up regulated by E2 in estrogen receptor-positive breast cancer lines.,similarity:Belongs to the exonucl |
| Subcellular location | Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body. |
| Expression | Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines. |
Additional Images
No image
Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
No image
No image
No image
: AO-06-ES15420-50
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package