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Antibody Product Overview
| ELK.No | ES15433 |
| Product name | IQEC1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9922 |
| Human Swiss-Prot | Q6DN90 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IQEC1 |
| Fields | >>Endocytosis |
| Gene name | IQSEC1 ARFGEP100 BRAG2 KIAA0763 |
| Protein name | IQEC1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 232227 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R0S2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human IQEC1 AA range: 693-743 |
| Specificity | This antibody detects endogenous levels of IQEC1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.264% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | |
| Function | function:In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.,similarity:Belongs to the BRAG family.,similarity:Contains 1 IQ domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subcellular location:At steady state, may be preferentially cytosolic.,subunit:Interacts with ARF6.,tissue specificity:Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis., |
| Subcellular location | Cytoplasm . Nucleus . Cell junction, synapse, postsynaptic density . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . At steady state, may be preferentially cytosolic. |
| Expression | Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis. |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15433-50
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