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Antibody Product Overview
| ELK.No | ES15466 |
| Product name | IMPCT rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 55364 |
| Human Swiss-Prot | Q9P2X3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IMPCT |
| Fields | |
| Gene name | IMPACT |
| Protein name | IMPCT |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 16210 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O55091 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 497198 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5GFD9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human IMPCT AA range: 123-173 |
| Specificity | This antibody detects endogenous levels of IMPCT at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 35kD |
| Observed band (KD) | |
| Background | |
| Function | function:Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis.,miscellaneous:In contrast to the mouse or rabbit ortholog, the IMPACT locus is not imprinted in human.,similarity:Belongs to the IMPACT family.,similarity:Contains 1 RWD domain.,subunit:Interacts with GCN1/GCN1L1.,tissue specificity:Widely expressed. Expressed at high level in brain., |
| Subcellular location | Cytoplasm . |
| Expression | Widely expressed. Expressed at high level in brain. |
Additional Images
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Western blot analysis of lysates from AD293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15466-100
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