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Antibody Product Overview
| ELK.No | ES15529 |
| Product name | IFI30 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) (Legumaturain) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10437 |
| Human Swiss-Prot | P13284 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IFI30 |
| Fields | >>Antigen processing and presentation |
| Gene name | IFI30 GILT IP30 |
| Protein name | IFI30 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 65972 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9ESY9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 290644 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q499T2 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human IFI30 AA range: 3-53 |
| Specificity | This antibody detects endogenous levels of IFI30 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.06% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 25kD |
| Background | The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008], |
| Function | function:Cleaves disulfide bonds in proteins by reduction. May facilitate the complete unfolding of proteins destined for lysosomal degradation. May be involved in MHC class II-restricted antigen processing.,induction:Expressed constitutively in antigen-presenting cells and induced by IFN-gamma in other cell types.,PTM:N-glycosylated. Sugar chains contain mannose-6-phosphate.,similarity:Belongs to the GILT family., |
| Subcellular location | Secreted . Lysosome . |
| Expression | Lung,Skin, |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15529-50
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