| ELK.No | ES15533 |
| Product name | IF122 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 55764 |
| Human Swiss-Prot | Q9HBG6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IF122 |
| Fields | |
| Gene name | IFT122 SPG WDR10 WDR140 |
| Protein name | IF122 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 81896 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6NWV3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human IF122 AA range: 956-1006 |
| Specificity | This antibody detects endogenous levels of IF122 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 137kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Mutations in this gene cause cranioectodermal dysplasia-1. A related pseudogene is located on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013], |
| Function | similarity:Contains 7 WD repeats.,tissue specificity:Expressed in many tissues. Predominant expression in testis and pituitary., |
| Subcellular location | Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Localizes to photoreceptor connecting cilia. . |
| Expression | Expressed in many tissues. Predominant expression in testis and pituitary. |

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