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Antibody Product Overview
| ELK.No | ES15535 |
| Product name | IDI1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3422 |
| Human Swiss-Prot | Q13907 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IDI1 |
| Fields | >>Terpenoid backbone biosynthesis;>>Metabolic pathways |
| Gene name | IDI1 |
| Protein name | IDI1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 319554 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P58044 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 89784 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O35760 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human IDI1 AA range: 103-153 |
| Specificity | This antibody detects endogenous levels of IDI1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 25kD |
| Observed band (KD) | |
| Background | IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:Isopentenyl diphosphate = dimethylallyl diphosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).,pathway:Isoprenoid biosynthesis; dimethylallyl-PP biosynthesis; dimethylallyl-PP from isopentenyl-PP: step 1/1.,similarity:Belongs to the IPP isomerase type 1 family.,subunit:Monomer., |
| Subcellular location | Peroxisome . |
| Expression |
Additional Images
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Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15535-50
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