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Antibody Product Overview
| ELK.No | ES15696 |
| Product name | HMGB3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3149 |
| Human Swiss-Prot | O15347 |
| Source | Rabbit |
| Isotype | IgG |
| Target | HMGB3 |
| Fields | |
| Gene name | HMGB3 HMG2A HMG4 |
| Protein name | HMGB3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 15354 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O54879 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human HMGB3 AA range: 123-173 |
| Specificity | This antibody detects endogenous levels of HMGB3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 22kD |
| Observed band (KD) | |
| Background | This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], |
| Function | function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,tissue specificity:Expressed predominantly in placenta., |
| Subcellular location | Nucleus . Chromosome . Cytoplasm . |
| Expression | Expressed predominantly in placenta. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15696-100
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