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Antibody Product Overview
| ELK.No | ES15759 |
| Product name | HIP1R rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9026 |
| Human Swiss-Prot | O75146 |
| Source | Rabbit |
| Isotype | IgG |
| Target | HIP1R |
| Fields | |
| Gene name | HIP1R HIP12 KIAA0655 |
| Protein name | HIP1R |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 29816 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JKY5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human HIP1R AA range: 554-604 |
| Specificity | This antibody detects endogenous levels of HIP1R at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 117kD |
| Observed band (KD) | |
| Background | |
| Function | domain:The talin-like domain binds F-actin.,function:Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.,similarity:Belongs to the SLA2 family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 1 I/LWEQ domain.,subcellular location:Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region.,subunit:Interacts with actin. Does not interact with huntingtin (By similarity). Interacts with CLTB and HIP1.,tissue specificity:Brain, heart, kidney, pancreas, and liver, but not in lung or placenta., |
| Subcellular location | Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region. |
| Expression | Brain, heart, kidney, pancreas, and liver, but not in lung or placenta. |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15759-50
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