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Antibody Product Overview
| ELK.No | ES16205 |
| Product name | GFPT1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2673 |
| Human Swiss-Prot | Q06210 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GFPT1 |
| Fields | >>Alanine, aspartate and glutamate metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of nucleotide sugars;>>Insulin resistance;>>Diabetic cardiomyopathy |
| Gene name | GFPT1 GFAT GFPT |
| Protein name | GFPT1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14583 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P47856 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 297417 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P82808 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human GFPT1 AA range: 198-248 |
| Specificity | This antibody detects endogenous levels of GFPT1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 77kD |
| Observed band (KD) | |
| Background | This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008], |
| Function | catalytic activity:L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.,function:Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.,pathway:Nucleotide-sugar biosynthesis; UDP-N-acetyl-D-glucosamine biosynthesis; D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.,similarity:Contains 1 glutamine amidotransferase type-2 domain.,similarity:Contains 2 SIS domains.,subunit:Homotetramer .,tissue specificity:Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle., |
| Subcellular location | cytosol,extracellular exosome, |
| Expression | Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. |
Additional Images
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Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16205-100
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