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Antibody Product Overview
| ELK.No | ES1638 |
| Product name | ALDH3B1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | ALDH3B1; ALDH7; Aldehyde dehydrogenase family 3 member B1; Aldehyde dehydrogenase 7 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 221 |
| Human Swiss-Prot | P43353 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ALDH3B1 |
| Fields | >>Glycolysis / Gluconeogenesis;>>Histidine metabolism;>>Tyrosine metabolism;>>Phenylalanine metabolism;>>beta-Alanine metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Metabolic pathways |
| Gene name | ALDH3B1 |
| Protein name | Aldehyde dehydrogenase family 3 member B1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q80VQ0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ALDH3B1. AA range:51-100 |
| Specificity | ALDH3B1 Polyclonal Antibody detects endogenous levels of ALDH3B1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 52kD |
| Background | This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014], |
| Function | catalytic activity:An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,tissue specificity:Highest expression in kidney and lung., |
| Subcellular location | Cell membrane ; Lipid-anchor . Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm. |
| Expression | Highest expression in kidney and lung. |
Additional Images
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Western Blot analysis of various cells using ALDH3B1 Polyclonal Antibody diluted at 1:500
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ALDH3B1 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HUVEC cells, using ALDH3B1 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from RAW264.7cells using ALDH3B1 antibody.
: AO-06-ES1638-50
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