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Antibody Product Overview
| ELK.No | ES16397 |
| Product name | FKB10 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 60681 |
| Human Swiss-Prot | Q96AY3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FKB10 |
| Fields | |
| Gene name | FKBP10 FKBP65 PSEC0056 |
| Protein name | FKB10 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14230 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q61576 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human FKB10 AA range: 339-389 |
| Specificity | This antibody detects endogenous levels of FKB10 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 64kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009], |
| Function | catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin, but not by cyclosporin A.,function:PPIases accelerate the folding of proteins during protein synthesis.,PTM:Glycosylated and phosphorylated.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 2 EF-hand domains.,similarity:Contains 4 PPIase FKBP-type domains., |
| Subcellular location | Endoplasmic reticulum lumen . |
| Expression |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16397-50
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