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Antibody Product Overview
| ELK.No | ES1646 |
| Product name | AMPD2 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | AMPD2; AMP deaminase 2; AMP deaminase isoform L |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 271 |
| Human Swiss-Prot | Q01433 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AMPD2 |
| Fields | >>Purine metabolism;>>Metabolic pathways;>>Nucleotide metabolism |
| Gene name | AMPD2 |
| Protein name | AMP deaminase 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 109674 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9DBT5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 362015 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q02356 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AMPD2. AA range:131-180 |
| Specificity | AMPD2 Polyclonal Antibody detects endogenous levels of AMPD2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 100kD |
| Background | The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012], |
| Function | catalytic activity:AMP + H(2)O = IMP + NH(3).,function:AMP deaminase plays a critical role in energy metabolism.,pathway:Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.,similarity:Belongs to the adenosine and AMP deaminases family.,subunit:Homotetramer.,tissue specificity:Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes., |
| Subcellular location | cytosol, |
| Expression | Highly expressed in cerebellum. |
Additional Images
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Western Blot analysis of various cells using AMPD2 Polyclonal Antibody
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Western blot analysis of the lysates from HeLa cells using AMPD2 antibody.
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: AO-06-ES1646-100
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