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Antibody Product Overview
| ELK.No | ES16474 |
| Product name | FHL5 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9457 |
| Human Swiss-Prot | Q5TD97 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FHL5 |
| Fields | |
| Gene name | FHL5 ACT |
| Protein name | FHL5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 57756 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9WTX7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 297954 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6AXT1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FHL5 AA range: 129-179 |
| Specificity | This antibody detects endogenous levels of FHL5 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 31kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Polymorphisms in this gene may be associated with susceptibility for migraine headaches. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Apr 2016], |
| Function | function:May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.,similarity:Contains 4 LIM zinc-binding domains.,subcellular location:Nuclei of round and elongated spermatids.,subunit:Interacts with CREM via the third LIM domain.,tissue specificity:Testis-specific (at protein level)., |
| Subcellular location | Nucleus . Nuclei of round and elongated spermatids. |
| Expression | Testis-specific (at protein level). |
Additional Images
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Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16474-50
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