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Antibody Product Overview
| ELK.No | ES16493 |
| Product name | FDFT rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2222 |
| Human Swiss-Prot | P37268 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FDFT |
| Fields | >>Steroid biosynthesis;>>Metabolic pathways |
| Gene name | FDFT1 |
| Protein name | FDFT |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14137 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P53798 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29580 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q02769 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FDFT AA range: 11-61 |
| Specificity | This antibody detects endogenous levels of FDFT at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 46kD |
| Observed band (KD) | |
| Background | This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:2 farnesyl diphosphate = diphosphate + presqualene diphosphate.,catalytic activity:Presqualene diphosphate + NAD(P)H = squalene + diphosphate + NAD(P)(+).,cofactor:Magnesium.,pathway:Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl-PP: step 1/3.,similarity:Belongs to the phytoene/squalene synthetase family.,subunit:Monomer., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Expression | Widely expressed. |
Additional Images
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Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16493-100
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