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Antibody Product Overview
| ELK.No | ES16494 |
| Product name | FCGRN rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2217 |
| Human Swiss-Prot | P55899 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FCGRN |
| Fields | |
| Gene name | FCGRT FCRN |
| Protein name | FCGRN |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14132 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q61559 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29558 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P13599 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FCGRN AA range: 146-196 |
| Specificity | This antibody detects endogenous levels of FCGRN at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 40kD |
| Observed band (KD) | |
| Background | This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009], |
| Function | function:Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.,similarity:Belongs to the immunoglobulin superfamily.,subunit:FcRn complex consist of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . Endosome membrane . |
| Expression | Expressed in full-term placenta, heart, lung, liver, muscle, kidney, pancreas, and both fetal and adult small intestine. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16494-50
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