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Antibody Product Overview
| ELK.No | ES16526 |
| Product name | FAN1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 22909 |
| Human Swiss-Prot | Q9Y2M0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FAN1 |
| Fields | >>Fanconi anemia pathway |
| Gene name | FAN1 KIAA1018 MTMR15 |
| Protein name | FAN1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 330554 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q69ZT1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human FAN1 AA range: 801-851 |
| Specificity | This antibody detects endogenous levels of FAN1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 112kD |
| Observed band (KD) | |
| Background | This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016], |
| Function | similarity:Belongs to the MTMR15 family., |
| Subcellular location | Nucleus . Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2 (PubMed:20603015, PubMed:20603016). Localizes to stalled replication forks via its UBZ4-type zinc finger (PubMed:20935496). . |
| Expression |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16526-50
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