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Antibody Product Overview
| ELK.No | ES16539 |
| Product name | FADS3 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3995 |
| Human Swiss-Prot | Q9Y5Q0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FADS3 |
| Fields | |
| Gene name | FADS3 CYB5RP |
| Protein name | FADS3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 60527 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JJE7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 286922 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q8K1P9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FADS3 AA range: 60-110 |
| Specificity | This antibody detects endogenous levels of FADS3 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 49kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008], |
| Function | domain:The histidine box domains may contain the active site and/or be involved in metal ion binding.,similarity:Belongs to the fatty acid desaturase family.,similarity:Contains 1 cytochrome b5 heme-binding domain.,tissue specificity:Has been found in heart, liver, lung, uterus, and brainstem., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Expression | Highly expressed in various organs and tissues including liver, kidney, brain, lung, pancreas, testis, ovary and skeletal muscle (at protein level). |
Additional Images
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Western blot analysis of lysates from VEC cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16539-50
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