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Antibody Product Overview
| ELK.No | ES16650 |
| Product name | EXTL2 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2135 |
| Human Swiss-Prot | Q9UBQ6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | EXTL2 |
| Fields | >>Glycosaminoglycan biosynthesis - heparan sulfate / heparin;>>Metabolic pathways |
| Gene name | EXTL2 EXTR2 |
| Protein name | EXTL2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 58193 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9ES89 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human EXTL2 AA range: 141-191 |
| Specificity | This antibody detects endogenous levels of EXTL2 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 36kD |
| Observed band (KD) | |
| Background | |
| Function | catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,function:Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.,online information:Exostosin-like 2,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 47 family.,subcellular location:A soluble form is found in the serum.,tissue specifi |
| Subcellular location | Endoplasmic reticulum membrane ; Single-pass type II membrane protein .; [Processed exostosin-like 2]: Secreted. A soluble form is found in the serum. |
| Expression | Ubiquitous. |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16650-100
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