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Antibody Product Overview
| ELK.No | ES16679 |
| Product name | ERP29 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10961 |
| Human Swiss-Prot | P30040 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ERP29 |
| Fields | >>Protein processing in endoplasmic reticulum |
| Gene name | ERP29 C12orf8 ERP28 |
| Protein name | ERP29 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67397 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P57759 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 117030 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P52555 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human ERP29 AA range: 141-191 |
| Specificity | This antibody detects endogenous levels of ERP29 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 29kD |
| Observed band (KD) | |
| Background | This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| Function | function:Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Part a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.,tissue specificity:Ubiquitous. Mostly expressed in secretory tissues., |
| Subcellular location | Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Expression | Ubiquitous. Mostly expressed in secretory tissues. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16679-50
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