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Antibody Product Overview
| ELK.No | ES16828 |
| Product name | EAA4 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (Solute carrier family 1 member 6) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6511 |
| Human Swiss-Prot | P48664 |
| Source | Rabbit |
| Isotype | IgG |
| Target | EAA4 |
| Fields | >>Synaptic vesicle cycle;>>Glutamatergic synapse;>>Spinocerebellar ataxia |
| Gene name | SLC1A6 EAAT4 |
| Protein name | EAA4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20513 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O35544 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 84012 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O35921 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human EAA4 AA range: 320-370 |
| Specificity | This antibody detects endogenous levels of EAA4 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.118% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | |
| Function | function:Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,tissue specificity:Brain. Expressed densely and selectively in cell bodies of Purkinje cells., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Brain. Expressed densely and selectively in cell bodies of Purkinje cells. |
Additional Images
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Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16828-50
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