DUS15 rabbit pAb

DUS15 rabbit pAb

AO-06-ES16879-100

DUS15 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES16879
Product nameDUS15 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB
Other name
Size100μL
Unit price ($)248
Human gene ID128853
Human Swiss-ProtQ9H1R2
SourceRabbit
IsotypeIgG
TargetDUS15
Fields
Gene nameDUSP15 C20orf57 VHY
Protein nameDUS15
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID252864
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ8R4V2
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human DUS15 AA range: 15-65
SpecificityThis antibody detects endogenous levels of DUS15 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)32kD
Observed band (KD)
BackgroundThe protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
Functioncatalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,caution:Although assigned as two separate genes (c20orf57 and DUSP15), it is probable that C20orf57 does not exist by itself and is a part of the DUSP15 gene.,PTM:Isoform 3 is N-myristoylated.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Highly expressed in testis.,
Subcellular locationCytoplasm .; [Isoform 3]: Cell membrane; Lipid-anchor; Cytoplasmic side.
ExpressionHighly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334).

Additional Images

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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16879-100
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