| ELK.No | ES16890 |
| Product name | DSCR3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10311 |
| Human Swiss-Prot | O14972 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DSCR3 |
| Fields | |
| Gene name | DSCR3 DCRA DSCRA |
| Protein name | DSCR3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13185 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O35075 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human DSCR3 AA range: 163-213 |
| Specificity | This antibody detects endogenous levels of DSCR3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 33kD |
| Observed band (KD) | |
| Background | The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008], |
| Function | similarity:Belongs to the VPS26 family.,tissue specificity:Ubiquitously expressed., |
| Subcellular location | Endosome . |
| Expression | Ubiquitously expressed. |

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