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Antibody Product Overview
| ELK.No | ES16894 |
| Product name | DRP2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Dystrophin-related protein 2 (DRP-2) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 1821 |
| Human Swiss-Prot | Q13474 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DRP2 |
| Fields | |
| Gene name | DRP2 |
| Protein name | DRP2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13497 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q05AA6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 66027 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9EPA0 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human DRP2 AA range: 437-487 |
| Specificity | This antibody detects endogenous levels of DRP2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.245% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010], |
| Function | function:Possibly involved in membrane-cytoskeleton interactions of the central nervous system.,similarity:Contains 1 WW domain.,similarity:Contains 1 ZZ-type zinc finger.,similarity:Contains 2 spectrin repeats.,tissue specificity:Brain and spinal cord; very low levels in eye, ovary, epididymis and testis; not in cardiac and skeletal muscle., |
| Subcellular location | Cell junction, synapse, postsynaptic density . Cell projection, dendrite . Perikaryon . Cell membrane ; Peripheral membrane protein . Detected in Schwann cells at periaxonal myelin membranes. . |
| Expression | Detected in fetal brain. |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16894-50
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