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Antibody Product Overview
| ELK.No | ES16904 |
| Product name | DPYL3 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 1809 |
| Human Swiss-Prot | Q14195 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DPYL3 |
| Fields | |
| Gene name | DPYSL3 CRMP4 DRP3 ULIP ULIP1 |
| Protein name | DPYL3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 22240 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q62188 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25418 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q62952 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human DPYL3 AA range: 240-290 |
| Specificity | This antibody detects endogenous levels of DPYL3 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.179% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 65kD |
| Background | |
| Function | function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subcellular location:Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5 (By similarity). Interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.,tissue specificity:Mainly in heart and skeletal muscle. Also expressed strongly in fetal brain and spinal cord., |
| Subcellular location | Cytoplasm . Cell projection, growth cone . Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. . |
| Expression | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
Additional Images
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Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16904-100
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