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DARPP-32 (phospho-Ser97) rabbit pAb
AO-06-ES17020-50
Antibody Product Overview
| ELK.No | ES17020 |
| Product name | DARPP-32 (phospho-Ser97) rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB |
| Other name | Protein phosphatase 1 regulatory subunit 1B (DARPP-32) (Dopamine- and cAMP-regulated neuronal phosphoprotein) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 84152 |
| Human Swiss-Prot | Q9UD71 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DARPP-32 |
| Fields | >>cAMP signaling pathway;>>Dopaminergic synapse;>>Cocaine addiction;>>Amphetamine addiction;>>Alcoholism |
| Gene name | PPP1R1B DARPP32 |
| Protein name | DARPP-32 (Ser97) |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 19049 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q60829 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 360616 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6J4I0 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized phosho peptide around human DARPP-32 (Ser97) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat DARPP-32 (phospho-Ser97) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 30kD |
| Background | This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011], |
| Function | function:Inhibitor of protein-phosphatase 1.,PTM:Dopamine- and cyclic AMP-regulated neuronal phosphoprotein.,PTM:Phosphorylation of Thr-34 is required for activity.,similarity:Belongs to the protein phosphatase inhibitor 1 family., |
| Subcellular location | Cytoplasm. |
| Expression | Adipose tissue,Brain,Cerebellum,Colon,Ovary, |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17020-50
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