Français
English
Antibody Product Overview
| ELK.No | ES1707 |
| Product name | Arp3 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10096 |
| Human Swiss-Prot | P61158 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Arp3 |
| Fields | >>Endocytosis;>>Tight junction;>>Fc gamma R-mediated phagocytosis;>>Regulation of actin cytoskeleton;>>Bacterial invasion of epithelial cells;>>Pathogenic Escherichia coli infection;>>Shigellosis;>>Salmonella infection;>>Yersinia infection |
| Gene name | ACTR3 |
| Protein name | Actin-related protein 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 74117 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q99JY9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 81732 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4V7C7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ACTR3. AA range:369-418 |
| Specificity | Arp3 Polyclonal Antibody detects endogenous levels of Arp3 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 47kD |
| Background | The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013], |
| Function | function:Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.,similarity:Belongs to the actin family.,similarity:Belongs to the actin family. ARP3 subfamily.,subunit:Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1., |
| Subcellular location | Cytoplasm, cytoskeleton . Cell projection . Nucleus . In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554). |
| Expression | Brain,Cajal-Retzius cell,T-cell, |
Additional Images
No image
Western Blot analysis of various cells using Arp3 Polyclonal Antibody
No image
Western Blot analysis of K562 cells using Arp3 Polyclonal Antibody
No image
Western blot analysis of lysates from Jurkat and RAW264.7 cells, using ACTR3 Antibody. The lane on the right is blocked with the synthesized peptide.
No image
Western blot analysis of the lysates from COLO205 cells using ACTR3 antibody.
: AO-06-ES1707-50
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package