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Antibody Product Overview
| ELK.No | ES17215 |
| Product name | CRTAP rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10491 |
| Human Swiss-Prot | O75718 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CRTAP |
| Fields | |
| Gene name | CRTAP CASP |
| Protein name | CRTAP |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56693 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CYD3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human CRTAP AA range: 65-115 |
| Specificity | This antibody detects endogenous levels of CRTAP at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 44kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. [provided by RefSeq, Jul 2008], |
| Function | disease:Defects in CRTAP are the cause of osteogenesis imperfecta type 2B (OI-2B) [MIM:610854]. OI-2B is an autosomal recessive form of perinatal lethal OI. This form is designated OI-2B to distinguish it from the autosomal dominant form OI-2A.,disease:Defects in CRTAP are the cause of osteogenesis imperfecta type 7 (OI-7) [MIM:610682]. OI is a connective tissue disorder characterized by bone fragility and low bone mass. OI-7 is an autosomal recessive form of OI.,similarity:Belongs to the CRTAP/No55 family.,tissue specificity:Found in articular chondrocytes. Expressed in a variety of tissues., |
| Subcellular location | Secreted, extracellular space, extracellular matrix . |
| Expression | Found in articular chondrocytes. Expressed in a variety of tissues. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17215-50
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