CR1L rabbit pAb

CR1L rabbit pAb

AO-06-ES17235-100

CR1L rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES17235
Product nameCR1L rabbit pAb
ReactivityHuman; Mouse;Rat
ApplicationsWB
Other nameComplement component receptor 1-like protein (Complement C4b-binding protein CR-1-like protein)
Size100μL
Unit price ($)248
Human gene ID1379
Human Swiss-ProtQ2VPA4
SourceRabbit
IsotypeIgG
TargetCR1L
Fields>>Complement and coagulation cascades;>>Neutrophil extracellular trap formation;>>Hematopoietic cell lineage;>>Legionellosis;>>Leishmaniasis;>>Malaria;>>Tuberculosis
Gene nameCR1L
Protein nameCR1L
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID12946
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ64735
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID54243
Rat gene linkView Rat Gene
Rat Swiss-ProtQ63135
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human CR1L AA range: 45-95
SpecificityThis antibody detects endogenous levels of CR1L at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.163% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)60kD
Background
Functionsimilarity:Belongs to the receptors of complement activation (RCA) family.,similarity:Contains 8 Sushi (CCP/SCR) domains.,subcellular location:Predominantly found in association with the membrane fraction, but also located in the cytoplasm and in the supernatant.,subunit:Interacts with iC4 (methylamine-treated C4) but not for iC3 (methylamine-treated C3).,tissue specificity:Expressed in fetal liver and to a lesser extent in fetal spleen and thymus. Expression appears to be limited to hematopoietic and fetal lymphoid tissue.,
Subcellular locationCytoplasm . Membrane . Secreted . Predominantly found in association with the membrane fraction, but also located in the cytoplasm and in the supernatant.
ExpressionExpressed in fetal liver and to a lesser extent in fetal spleen and thymus. Expression appears to be limited to hematopoietic and fetal lymphoid tissue.

Additional Images

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Western blot analysis of lysates from VEC cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17235-100
: 10 Produits
Hurry! only 10 items left in stock.

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