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Antibody Product Overview
| ELK.No | ES17349 |
| Product name | CNIH2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 254263 |
| Human Swiss-Prot | Q6PI25 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CNIH2 |
| Fields | |
| Gene name | CNIH2 CNIL |
| Protein name | CNIH2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 12794 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O35089 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 361705 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5BJU5 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human CNIH2 AA range: 10-60 |
| Specificity | This antibody detects endogenous levels of CNIH2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 18kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012], |
| Function | function:Involved in the transport and maturation of proteins.,similarity:Belongs to the cornichon family., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). . |
| Expression | Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study). |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17349-100
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