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Antibody Product Overview
| ELK.No | ES17367 |
| Product name | CMBL rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 134147 |
| Human Swiss-Prot | Q96DG6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CMBL |
| Fields | >>Metabolic pathways |
| Gene name | CMBL |
| Protein name | CMBL |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 69574 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R1G2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 310201 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q7TP52 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human CMBL AA range: 136-186 |
| Specificity | This antibody detects endogenous levels of CMBL at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 27kD |
| Observed band (KD) | |
| Background | CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010], |
| Function | similarity:Belongs to the dienelactone hydrolase family., |
| Subcellular location | Cytoplasm, cytosol . |
| Expression | Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level). |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17367-100
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