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Antibody Product Overview
| ELK.No | ES17370 |
| Product name | CLPX rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10845 |
| Human Swiss-Prot | O76031 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CLPX |
| Fields | |
| Gene name | CLPX |
| Protein name | CLPX |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 270166 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JHS4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 300786 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5U2U0 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human CLPX AA range: 328-378 |
| Specificity | This antibody detects endogenous levels of CLPX at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 70kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015], |
| Function | function:ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of clpP.,similarity:Belongs to the clpX chaperone family.,subunit:Heterodimer of clpP and clpX.,tissue specificity:Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas., |
| Subcellular location | Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. |
| Expression | Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17370-50
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