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Antibody Product Overview
| ELK.No | ES17384 |
| Product name | CLC4E rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 26253 |
| Human Swiss-Prot | Q9ULY5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CLC4E |
| Fields | >>C-type lectin receptor signaling pathway;>>Tuberculosis |
| Gene name | CLEC4E CLECSF9 MINCLE UNQ218/PRO244 |
| Protein name | CLC4E |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56619 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9R0Q8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 450223 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q67EQ1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human CLC4E AA range: 46-96 |
| Specificity | This antibody detects endogenous levels of CLC4E at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 24kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008], |
| Function | function:May play a role in the response to inflammatory stimuli in peritoneal macrophages. May be involved in immune surveillance processes under transcriptional control of CEBPB.,online information:Mincle,similarity:Contains 1 C-type lectin domain., |
| Subcellular location | Cell membrane ; Single-pass type II membrane protein . Cell projection, phagocytic cup . |
| Expression | Expressed in monocytes and macrophages. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17384-100
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