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Antibody Product Overview
| ELK.No | ES17529 |
| Product name | CE120 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 153241 |
| Human Swiss-Prot | Q8N960 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CE120 |
| Fields | |
| Gene name | CEP120 CCDC100 |
| Protein name | CE120 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 225523 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q7TSG1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human CE120 AA range: 335-385 |
| Specificity | This antibody detects endogenous levels of CE120 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 108kD |
| Observed band (KD) | |
| Background | This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009], |
| Function | function:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors.,similarity:Belongs to the CEP120 family.,subcellular location:Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.,subunit:Interacts with TACC2 and TACC3., |
| Subcellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. . |
| Expression |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17529-100
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